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대한생식의학회지 제28권 제4호 2010년
반복자연유산 환자에서 Antithrombin III 결핍증에 대한 연구
포천중문의과대학 산부인과학교실, 임상의학연구소
남윤성, 남윤성,차광렬,김남근,강명서,오도연
The Study of Antithrombin III Deficiency in Patients with Recurrent Spontaneous Abortion
Nam ys
Department of Obstetrics and Gynecology, Institute for Clinical Research
Objective: To analyze the antithrombin III deficiency in patients with recurrent spontaneous abortion. Material and Method: The blood samples were tested by chromogenic assay to evaluate the activity of antithrombin III. Results: There was only one case of antithrombin III deficiency. This patient experienced one neonatal death after delivery and one FDIU (fetal death in utero). And also this patient showed a lupus anticoagulant and the prolongation of PTT. Conclusions: Women with recurrent miscarriage who have no obvious identified cause should consider hematologic screening. Antithrombin III deficiency could be a cause of recurrent spontaneous abortion. But the incidence is very rare in Korean patients.
키워드 : Recurrent spontaneous abortion, Antithrombin III deficiency
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