논문 및 학회지

대한생식의학회지   제29권 제3호 2010년

비만 불임여성에 대한 임상적 고찰

포천중문 의과대학 산부인과학교실, 임상의학연구소

남윤성, 정창진,김남근,윤태기,차광렬

Clinical Consideration of Obese Infertile Women

Nam YS

Obstetrics and Gynecology, Institute for Clinical Research College of Medicine, Pocheon CHA Univ

Objective: To analyze the clinical characteristics of obese infertile women. Material and Method: Height, weight, body mass index, menstrual pattern, glucose, insulin, glucose / insulin ratio, dehydroepiandrosterone sulfate (DHEA-S), testosterone, free testosterone and plasminogen activator inhibitor (PAI-1) of 15 obese infertile women were tested. Results: Of 15 obese infertile women, the number of diabetes mellitus, hyperinsulinemia, and insulin resistance was 2 (13%), 2 (13%), 2 (13%), respectively. The incidence of increased DHEA-S, testosterone, and free testosterone was 7 (47%), 1 (7%), 6 (40%), respectively. Notably, all patients showed increased PAI-1. Conclusions: Obesity is associated with infertility as well as many kinds of health problems. Obesity is closely related to insulin resistance and it also causes hyperandrogenism. Increased PAI-1 is one of the important causes of thrombophilia. Consequently, in the workup of obese infertile patient, many aspects of health problems should be considered.

키워드 : Obesity, Infertility

교신저자 : ysnam@cha.ac.kr
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