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대한생식의학회지 제13권 제2호 2010년

체외수정과 배이식에 의한 임신성공예에 관한 연구

고려대학교 의과대학 산부인과학교실;고려대학교 의과대학 산부인과학교실;고려대학교 의과대학 산부인과학교실;고려대학교 의과대학 산부인과학교실;고려대학교 의과대학 산부인과학교실;성신여사대 생물학과;

구병삼;유동화;이규완;나중열;홍성봉;배인하;,

Pregnancies by In Vitro Fertilization and Embryo Transfer

Ku, Pyong-Sahm;Yoo, Dong-Wha;Lee, Kyu-Won;Rha, Joong-Yul;Hong, Sung-Bong;Bae, In-Ha;

Department of Obstetrics and Gynecology, Coffefe of Medicine, Korea University;Department of Obstetrics and Gynecology, Coffefe of Medicine, Korea University;Department of Obstetrics and Gynecology, Coffefe of Medicine, Korea University;Department of Obstetrics and Gynecology, Coffefe of Medicine, Korea University;Department of Obstetrics and Gynecology, Coffefe of Medicine, Korea University;;

We have reviewed 59 cases of patients amoung 65 cases who underwent IVF and ET with reasonable indications irom 1984 and the results as follows. 1. Major indications for IVF and ET were tubal factor (40.7%), unexplained infertility (25.4%), endometriosis (15.3%), failed AID and AIH (10.1 %), and sperm abnormality (8.5%). 2. For superovulation of human oocytes, l00mg of clomiphene citrate and 75 IU of HMG used. The monitoring of oocyte maturation was bone by ultrasound examination and serum 17-${\beta}$ estradiol, LH values. The peak $E_2$ value was 956.36${\pm}$702.13 pg/ml. 3. The oocytes were obtained by laparoscopy 24-36 hours after the injection of HCG. 4. The mean numbers of follicles at laparoscopy was 3.06 and the successful rate of laparoscopy was 79.7%. 5. And 165 follicles were aspirated from which 98 oocytes were recovered, 59.4% of all follicles had at least one oocyte aspirated. 21.4% of the eggs were mature, 52.0% were moderate, 26.5%. were immature. 6. 67.3% of oocytes were cleaved and were transferred at 4-6 cell stages. 7. Four pregnancies including one chemical pregnancy and one spontaneous abortion were established by ${\beta}$-subunit, u-hCG and ultrasound examinations.

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