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대한생식의학회지 제20권 제1호 2010년
정자 세척후 SWIM-UP 처치와 Percoll정자 처리방법의 자궁강내 인공수정술 후 임신 성공예후에 대한 비교 관찰
전남대학교 의과대학 산부인과학교실;전남대학교 의과대학 산부인과학교실;전남대학교 의과대학 산부인과학교실;
박현주;박현정;이여일;,
Comparison Between a Swim Up after Sperm Washing and a Percoll Gradient Technique for Intrauterine Insemination Outcome
Park, Hyun-Jue;Park, Hyun-Jeong;Lee, Yu-Il;
Department of Obstetrics and Gynecology, Chonnam University Medical School;Department of Obstetrics and Gynecology, Chonnam University Medical School;Department of Obstetrics and Gynecology, Chonnam University Medical School;
From September 1988 to August 1992, two different methods of preparing human sperm before intrauterine insemination(IUI) were compared using the semen samples of seventy-three infertile couples. The sperms were prepared by a swim-up after sperm washing or by a continuous percoll gradient technique. Fourteen of 35 women conceived during IUI cycles using a sperm washing and swim-up method (40%), and 12 of 38 women conceived during IUI cycles using a percoll gradient technique(31.6%). Among the group with male infertile etiologic factor only, one of 5 women conceived during sperm washing and swim-up cycles(20%); one of 4 women conceived during percoll gradient cycles(25%). On the contrary, among the group with cervical factor only, six of 10 women conceived during sperm washing and swim-up cycles (60%) ; Five of 17 women conceived during percoll gradient cycles(29.4%). It is suggested that sperm separation by sperm washing ar -up is a useful technique for intrauterine insemination in cervical infertility, and sperm separation in percoll gradient appears to be more valuable for intrauterine insemination of male subfertility.
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