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대한생식의학회지 제27권 제1호 2010년
체외수정시술시 Sequential ET의 효용성에 관한 연구
인제대학교 의과대학 일산백병원 산부인과;인천 서울산부인과 불임크리닉;인천 서울산부인과 불임크리닉;
정병준;김종식;송현진;,
Effect of Sequential Embryo Transfer in vitro Fertilization
Jung, Byeong-Jun;Kim, Jong-Sik;Song, Hyun-Jin;
Department of Obstetrics & Gynecology, College of Medicine, University of Inje, Ilsan Paik Hospital;Infertility Clinic, Seoul Obstetrics & Gynecology, Inchon;Infertility Clinic, Seoul Obstetrics & Gynecology, Inchon;
Objective: The objective of this study is to influence of sequential embryo transfers in an invitro fertilization was examined. Method: After in vitro fertilization, a maximum of 6 fertilized oocytes was enrolled in this study. At day 3 after an oocytes retrieval, embryos with good quality were transferred (mean 4.9), remaining embryos (mean 2.0/cycle) were cryopreserved at blastocyst stage (Group 1). At day 5 after oocytes collection, second a embryo transfer (mean 1.2/cycle) was performed, if one of these embryos had reached the blastocyst stage (Group 2) using P1 supplemented with 10 SSS and 30% Follicular fluid. No statistical difference in the pregnancy rate could be seen between the group without a second embryo transfer (n=21; 28.6%) and the group with a second transfer (n=52; 28.8%). Results: The incidence of multiple pregnancy rate per embryo transfer was not statistically different between both group and no high-rank multiple pregnancy (greater than triplete) were observed (0.9%, 15.4%, respectively, p=0.74,
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