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대한생식의학회지 제36권 제1호 2010년
대구, 경북 지역 한국인 다낭성 난소 증후군 환자의 임상 양상
경북대학교 병원 산부인과
배진영, 김미연, 성수경, 오정은, 전상식, 이택후*,
Clinical Characteristics of Korean Daegu • Kyungpook PCOS Women
Jin Young Bae, Mi Yeon Kim, Su Kyung Sung, Jeong Eun Oh, Sang Sik Chun, Taek Hoo Lee*
Kyungpook National University Hospital Department of Obstetrics and Gynecology
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Objective: PCOS is one of the most common endocrine disorder affecting reproductive age women. It shows wide range of reproductive and metabolic manifestations. This study was to determine the differences of clinical and laboratory characteristics between adolescent and adult Korean Daegu • Kyungpook PCOS patients. We also compared clinical and laboratory values of Korean PCOS patients to Turkish and American PCOS patients. Methods: 88 cases were diagnosed and enrolled as PCOS patients, based on 2003 Rotterdam criteria, who visited KNUH Reproductive Endocrinology division between Jan. 2000 and Apr. 2008. We retrospectively reviewed clinical characteristics, serum hormone levels, ultrasono-graphic findings. And we divided into 2 groups, adolescent and adult. We analyzed them with Chi-square test and Student's t-test statistically. Results: There were no statistically significant differences between adult and adolescent Korean PCOS patients. The prevalence of hyperandrogenism such as facial acne or hirsutism, obesity, and insulin resistance of Korean PCOS women was significantly lower than Turkish and American PCOS women. Conclusion: From the results of this study, we can suggest that it is sure that there are differences of clinical and laboratory characteristics of PCOS patients between races. Genetic background, dietary habits and life style affect the expression of clinical symptoms of PCOS. But we could not find out the difference between adolescent and adult PCOS patients of same race. It might be due to the limitation of small patient number and narrow range of age distribution. So, there must be large scale and multi-center and multi-regional study.
키워드 : Korean, PCOS, Clinical characteristics, Laboratory characteristics
교신저자 : chnkim@amc.seoul.kr
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