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대한생식의학회지 제17권 제2호 2010년
남성불임 환자에서 Tray Agglutination Test 및 Indirect Immunobead Test를 이용한 항정자항체에 관한 연구
연세대학교 의과대학 비뇨기과학교실;연세대학교 의과대학 비뇨기과학교실;제일병원 비뇨기과;
김철수;이무상;홍재엽;,
Antisperm Antibodies in Infertile Males as Detected by Tray Agglutination Test and Indirect Immunobead Test
Kim, Cheol-Soo;Lee, Moo-Sang;Hong, Jae-Yup;
Department of Urology, College of Medicine, Yonsei University;Department of Urology, College of Medicine, Yonsei University;Cheil General Hospital;
Sera from 95 infertile males males were assayed for antisperm antibodies using the Tray Agglutination Test(TAT) and indirect Immunobead Test(IBT). The correlation between antisperm antibodies and seminal analysis in infertile men was evaluated, and the TAT was compared with new indirect IBT. The results were obtained as follows. 1. Positive rate for antisperm antibodies was high in azoospermia, oligoasthenospermia, pyo-spermia, in order, Especially in obstructive azoospermia, the rate was the highest in both methods 2. Positive rates for antisperm antibodies in TAT was higher than indirect IBT. 3. Among the isotypes of the immunoglobulins, IgG were most prevalent. IgG and IgA were bound predominantly to the head and IgM predominantly to the tail up.
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