논문 및 학회지

대한생식의학회지   제18권 제1호 2010년

면역화학적 방법에 의한 정자결함 검색

연세대학교 의과대학 비뇨기과학교실;연세대학교 의과대학 비뇨기과학교실;

김세중;이무상;,

Evaluation of the Spermatozoal Defect with Immunochemical Method

Kim, Se-Joong;Lee, Moo-Sang;

Department of Urology, Yonsei University College of Medicine;Department of Urology, Yonsei University College of Medicine;

Although many therapies have been advocated in the treatment of idiopathic male infertility, the results of treatment are poor. This probably seems to be due to a lack of one or more proteins constituting the key structures of the spermatozoa. We evaluated the functional structures of the spermatozoa in 11 infertile patients whose semen showed severe oligoasthenozoospermia with immunochemical method and found a case with spermatozoa lacking acrosin. Evaluation of the spermatozoal defect with immunochemical method is desirable in patients with severe oligoasthenozoospermia, especially in cases unresponsive to medical therapy.

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