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대한생식의학회지 제18권 제1호 2010년
습관성 유산의 원인적 분류
한양대학교 의과대학 산부인과학교실;한양대학교 의과대학 산부인과학교실;한양대학교 의과대학 산부인과학교실;한양대학교 의과대학 산부인과학교실;한양대학교 의과대학 산부인과학교실;한양대학교 의과대학 산부인과학교실;
박문일;이기헌;정성로;이재억;문형;김두상;,
Etiologic Classification of Recurrent Spontaneous Abortion
Park, Moon-Il;Lee, Ki-Hun;Chung, Sung-Ro;Lee, Jai-Auk;Moon, Hyung;Kim, Doo-Sang;
Department of Obstetrics and Gynecology, School of Medicine, Hanyang University;Department of Obstetrics and Gynecology, School of Medicine, Hanyang University;Department of Obstetrics and Gynecology, School of Medicine, Hanyang University;Department of Obstetrics and Gynecology, School of Medicine, Hanyang University;Department of Obstetrics and Gynecology, School of Medicine, Hanyang University;Department of Obstetrics and Gynecology, School of Medicine, Hanyang University;
Etiologic classification was performed in 155 patients with recurrent spontaneous abortion history. The incidence was 9.3% among 1658 pregnant women at Hanyang university hospital during the same period. In etiologic classification, 37 cases of on-going patients for diagnostic evaluation were excluded. Of the remained 118 patients, the patients with unknown etiology were 32 cases (27.1%), and 86 cases were classified into each etiologies using appropriate diagnostic modalities. Anatomic causes were the largest etiology, which revealed 46.6% (55 among 118 patients). The next etiology was immunologic cause, which revealed 24.6% (29 patients). Of the 86 patients who have at least one cause, 40.7% (35 among 86) have two or more etiologies. Furthermore, six cases (7%) have 3 combined etiologies. The uterine synechia and/or incompetent internal os of the cervix, namaly anatomic causes, revealed highest combination ratio than other etilogies. The popular abortion technique in Korea, D&C, seems to be main factors for these anatmic causes. The combined causes rather than single cause of recurrent spontaneous abortion were unique situation in Korea especially with anatomic etiologies. From this point of view, we think anatomic etiologies should be rule out first in the evaluation of the patients. For this purpose, we believe hysteroscopy would be helpful as a diagnostic work-up and treatment modality in the management of recurrent spontaneous abortion patients in Korea.
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