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대한생식의학회지 제22권 제3호 2010년
건국대학교 동물자원연구센터;
김남형;,
Cytoskeletal Alteration of Mammalian Oocytes During Meiotic Maturation, Fertilization and Parthenogenesis
Kim, Nam-Hyeong;
;
Microtubules and microfilaments are major cytoskeletal components in mammalian ova that provide the framework for chromosomal movement and cellular division. Extensive changes of cytoskeletal organization occur during maturation and fertilization. The changes in cytoskeletons are essential for the normal meiotic maturation and for the formation of the biparental diploid genome of the embryo, and thus are repeated at each cell cycle during embryonic development. Disturbance of the cytoskeletal organization could result in abnormal gamete development and early embryonic death.
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