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대한생식의학회지 제24권 제3호 2010년
체외수정시술시 과배란유도 방법이 임신율에 미치는 영향
홍산부인과 불임클리닉;홍산부인과 불임클리닉;
홍정의;이지삼;,
Effects of Cotrolled Ovarian Hyperstimulation (COH) Protocols on Pregnancy and Delivery Rate in In-Vitro Fertilization and Embryo Transfer
Hong, J.E.;Lee, J.S.;
Infertility Clinic, Hong's OB/GY;Infertility Clinic, Hong's OB/GY;
A total of 55 patients with various etiologies of infertility particitated in a study comparing two regimens of controlled ovarian hyperstimulation (COH) with GnRH agonists and gonadotropins. Nineteen patients were given an ultra-short stimulation protocol when the agonist was administered for 3 day from Day 2 of the cycle. The remaining 36 patients were given a long stimulation protocol when the agonist was administered from the mid-luteal phase of the cycle preceding the stimulation cycle. The mean number of gonadotropins used per patient was not different between two groups. No significant differences were found in the mean number of oocytes recovered, fertilization rate and embryo cleavage rate between two groups. Pregnancy and delivery rates were higher in ultra-short protocol than in long protocol, but these were not significant. These results suggest that an ultra-short protocol is as effective as a long protocol in in-vitro fertilization and embryo transfer.
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