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대한생식의학회지 제27권 제2호 2010년
Fertilization Promoting Peptide가 사람 정자의 운동양태, 수정능력획득 및 첨체반응에 미치는 영향
한양대학교 자연과학대학 생명과학과, 을지병원 의과학연구소;을지병원 의과학연구소;을지병원 의과학연구소;을지병원 의과학연구소;을지대학교 의과대학 비뇨기과학교실;을지병원 의과학연구소, 을지대학교 의과대학 생리학교실;한양대학교 자연과학대학 생명과학과;
강희규;김묘경;김동훈;한성원;최도연;이호준;김문규;,
Effect of Fertilization Promoting Peptide on Kinematic Parameters, Capacitation and Acrosome Reaction in Human Spermatozoa
Kang, Hee-Gyoo;Kim, Myo-Kyung;Kim, Dong-Hoon;Han, Sung-Won;Choi, Do-Hyun;Lee, Ho-Joon;Kim, Moon-Kyoo;
Department of Life Science, College of Natural Sciences, Hanyang University, Eulji Medical Science Institute, Eulji Medical Center;Eulji Medical Science Institute, Eulji Medical Center;Eulji Medical Science Institute, Eulji Medical Center;Eulji Medical Science Institute, Eulji Medical Center;Department of Urology, School of Medicine, Eulji University;Eulji Medical Science Institute, Eulji Medical Center, Department of physiology, School of Medicine, Eulji University;Department of Life Science, College of Natural Sciences, Hanyang University;
Objective: This study has been carried out to evaluation the effect of fertilization promoting peptide (FPP) on the kinematic parameters, capacitation and acrosome reaction of the frozen-thawed human spermatozoa. Methods: After FPP treatment, we examined kinematic parameters, capacitation and acrosome reaction, using the methods of computer-aided sperm analysis (CASA) and chlortetracycline (CTC) fluorescence analysis. Results: We have obtained the evidence that FPP can promote the capacitation and inhibit the spontaneous acrosome reaction of frozen-thawed human spermatozoa in vitro. FPP (
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