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대한생식의학회지 제26권 제3호 2010년
체외수정시술시 배아이식 후 배아이식도관 말단부에서의 미세균주 배양율과 임상적 임신율과의 관계
연세대학교 의과대학 산부인과학교실, 성균관대학교 의과대학, 강북삼성병원 산부인과학교실
이경진, 배상욱, 김정연, 김진영, 이병석, 박기현, 조동제, 송찬호,
Incidence of microbial growth from the tip of the embryo transfer catheter after embryo transfer in relation to clinical pregnancy rate following in-vitro fertilization and embryo transfer.
Lee kj, Bai sw, Kim jy, Kim jy1, Lee bs, Park kh, Cho dj, Song ch
This study was performed prospectively at the time of transcervical embryo transfer following conventional in-vitro fertilization and intracytoplasmic sperm injection procedures. Sixty three patients were enrolled in this study. Microbiological cultures were performed on endocervical swabs and embryo transfer catheter tips. Positive microbial growths were observed from endocervical swabs in 45(71.4%) women and from catheter tips in 30(47.6%) women. There was no statistically significant difference seen in the mean number of oocytes fertilized or number and grade of embryos transferred between the group of patients without growth and the group of patients with positive microbial growth from catheter tips. The clinical pregnancy rate were 30.3% in the group of patients without growth and 13.3% in the group with positive microbial growth from catheter tips. This difference in clinical pregnancy rates was statistically significant. Our finding is that microbial contamination at embryo transfer may influence implantation rates. The major questions arising from our finding are whether eradication of endocervical micro-organisms is possible and whether their eradication will improve implantation rates.
키워드 : embryo transfer, endocervical organisms, transfer catheter
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